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reliable follow up of a small business. LEAPChem Highlights alpha-Arbutin
today!
Basic
Information of alpha-Arbutin
Chemical Name: alpha-Arbutin
Cas No.: 84380-01-8
Molecular Formula: C12H16O7
Chemical Structure:
Arbutin is a
glycoside; a glycosylated hydroquinone extracted from the bearberry plant in
the genus Arctostaphylos among many other medicinal plants, primarily in the
Ericaceae family. Applied topically, it inhibits tyrosinase and thus prevents
the formation of melanin. Arbutin is therefore used as a skin-lightening agent.
Very tiny amounts of arbutin are found in wheat, pear skins, and some other
foods. It is also found in Bergenia crassifolia. Arbutin was also produced by
an in vitro culture of Schisandra chinensis.
It works by slowly releasing hydroquinone
through hydrolysis, which in turn blocks Tyrosinase activity and reduces the
skin’s melanin (pigmentation) production. In cosmetics, this ingredient appears
in two different forms: Alpha-Arbutin or Beta-Arbutin. Due to patenting
concerns, most skin care products contain plant extracts that contain Arbutin
(e.g. bearberry, pear, blueberry), rather than pure Arbutin. Used in a variety
of cosmetics, particularly ones aimed at lightening the skin such as lotions, crèmes,
serums, cleansers, and spot treatments.
Bearberry extract is used in skin
lightening treatments designed for long term and regular use. An active agent
in brands of skin lightening preparations, it is more expensive than
traditional skin lightening ingredients like hydroquinone, which is now banned
in many countries. In vitro studies of human melanocytes exposed to arbutin at
concentrations below 300 μg/mL reported decreased tyrosinase activity and
melanin content with little evidence of cytotoxicity.
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If you are interested in alpha-Arbutin, click here to send an inquiry!
Make LEAPChem your pharmaceutical chemicals
long-term partner and contact
us today!
References:
https://en.wikipedia.org/wiki/Arbutin
https://www.ncbi.nlm.nih.gov/pubmed/15056856
https://www.ncbi.nlm.nih.gov/pubmed/8632348
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