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Basic
Information of Diclofenac sodium
Chemical Name: Diclofenac sodium
Cas No.: 15307-79-6
Molecular Formula: C14H11Cl2NO2
Chemical Structure:
Diclofenac (sold
under a number of trade names) is a nonsteroidal anti-inflammatory drug (NSAID)
taken or applied to reduce inflammation and as an analgesic reducing pain in
certain conditions. It is supplied as or contained in medications under a
variety of trade names. Diclofenac is used to treat pain, inflammatory
disorders, and dysmenorrhea.
Diclofenac and misoprostol combination is
used to relieve symptoms of arthritis (eg, osteoarthritis or rheumatoid
arthritis) in patients who may develop stomach ulcers from taking nonsteroidal
anti-inflammatory drugs (NSAIDs).
Diclofenac is a nonsteroidal
anti-inflammatory drug (NSAID), used to relieve symptoms of arthritis such as
inflammation, swelling, stiffness, and joint pain. Misoprostol is used to
decrease the chance of having stomach and intestinal ulcers.
Inflammatory disorders may include
musculoskeletal complaints, especially arthritis, rheumatoid arthritis,
polymyositis, dermatomyositis, osteoarthritis, dental pain, temporomandibular
joint (TMJ) pain, spondylarthritis, ankylosing spondylitis, gout attacks, and
pain management in cases of kidney stones and gallstones. An additional
indication is the treatment of acute migraines. Diclofenac is used commonly to
treat mild to moderate postoperative or post-traumatic pain, in particular when
inflammation is also present, and is effective against menstrual pain and
endometriosis.
Diclofenac is also available in topical
forms and has been found to be useful for osteoarthritis but not other types of
long-term musculoskeletal pain.
It may also help with actinic keratosis,
and acute pain caused by minor strains, sprains, and contusions (bruises).
In many countries, eye drops are sold to
treat acute and chronic nonbacterial inflammation of the anterior part of the
eyes (e.g., postoperative states). Diclofenac eye drops have also been used to
manage pain for traumatic corneal abrasion.
Diclofenac is often used to treat chronic
pain associated with cancer, in particular if inflammation is also present
(Step I of the World Health Organization (WHO) scheme for treatment of chronic
pain). Diclofenac can be combined with opioids if needed such as a fixed
combination of diclofenac and codeine.
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If you are interested in Diclofenac sodium, click here to send an inquiry!
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References:
https://en.wikipedia.org/wiki/Diclofenac
https://www.ncbi.nlm.nih.gov/pubmed/2670397
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445819/
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